Charles N Serhan Selected Research

Anti-Inflammatory Agents (Anti-Inflammatories)

1/2023	Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution.
1/2019	Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology.
1/2018	Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.
8/2004	A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils.
11/2002	Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Charles N Serhan Research Topics

Disease

218	Inflammation (Inflammations) 01/2024 - 01/2002
28	Peritonitis 10/2023 - 10/2002
27	Infections 01/2022 - 06/2005
17	Neoplasms (Cancer) 03/2024 - 04/2003
16	Pain (Aches) 10/2023 - 11/2003
11	Pneumonia (Pneumonitis) 12/2023 - 09/2002
7	Sepsis (Septicemia) 11/2019 - 10/2009
6	Obesity 01/2021 - 09/2012
6	Atherosclerosis 11/2017 - 10/2008
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 02/2004
5	COVID-19 01/2023 - 01/2020
5	Hypoxia (Hypoxemia) 01/2020 - 06/2002
4	Reperfusion Injury 01/2023 - 11/2009
4	Carcinogenesis 01/2021 - 08/2006
4	Neuralgia (Stump Neuralgia) 01/2021 - 04/2012
4	Colitis 11/2017 - 05/2005
4	Wounds and Injuries (Trauma) 12/2015 - 06/2013
4	Respiratory Hypersensitivity 01/2007 - 09/2002
3	Fibrosis (Cirrhosis) 01/2023 - 07/2015
3	Arthritis (Polyarthritis) 01/2023 - 01/2016
3	Thrombosis (Thrombus) 01/2022 - 01/2016
3	Lung Injury 01/2021 - 01/2013
3	Cytokine Release Syndrome 01/2021 - 01/2020
3	Stroke (Strokes) 11/2020 - 10/2003
3	Myocardial Infarction 01/2020 - 07/2015
3	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2018 - 11/2014
3	Acute Pain 01/2018 - 03/2011
3	Hyperalgesia 01/2018 - 03/2011
3	Postoperative Pain 01/2018 - 03/2011
3	Periodontitis 11/2017 - 12/2003
3	Ischemia 11/2017 - 10/2003
3	Body Weight (Weight, Body) 10/2017 - 05/2005
3	Edema (Dropsy) 01/2016 - 05/2010
3	Chronic Obstructive Pulmonary Disease (COPD) 12/2015 - 01/2013
3	Acute Lung Injury 11/2014 - 08/2009
3	Asthma (Bronchial Asthma) 01/2007 - 09/2002
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2023 - 07/2018

Drug/Important Bio-Agent (IBA)

120	LipidsIBA 01/2023 - 01/2002
45	LipoxinsIBA 01/2022 - 01/2002
32	resolvin D1IBA 10/2023 - 03/2007
27	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 01/2022 - 03/2005
27	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2019 - 01/2002
24	Docosahexaenoic AcidsIBA 01/2023 - 10/2003
21	CytokinesIBA 01/2022 - 10/2002
20	Eicosapentaenoic AcidIBA 01/2022 - 03/2005
20	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2021 - 06/2006
20	EicosanoidsIBA 01/2021 - 09/2002
19	lipoxin A4IBA 01/2022 - 01/2002
17	protectin D1IBA 01/2022 - 10/2005
16	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 10/2023 - 10/2005
15	AutacoidsIBA 01/2022 - 04/2003
15	ProstaglandinsIBA 01/2021 - 09/2002
14	LeukotrienesIBA 01/2021 - 09/2002
13	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 04/2003
13	ZymosanIBA 01/2021 - 09/2004
10	AcidsIBA 01/2022 - 12/2003
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2003
9	resolvin D2IBA 12/2023 - 10/2009
9	Arachidonic Acid (Vitamin F)IBA 01/2021 - 02/2004
8	CD59 AntigensIBA 01/2021 - 01/2009
8	7,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA 01/2021 - 04/2012
8	EnzymesIBA 12/2019 - 12/2003
7	MucinsIBA 10/2022 - 04/2011
7	Leukotriene B4IBA 01/2020 - 04/2003
6	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 01/2023 - 12/2003
6	Carbon MonoxideIBA 12/2018 - 06/2013
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 06/2006
5	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2023 - 11/2002
5	Analgesics (Analgesic Drugs)IBA 01/2023 - 05/2010
5	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021 - 06/2009
5	Interleukin-13IBA 01/2021 - 09/2002
5	ChemokinesIBA 01/2019 - 11/2006
5	MicroRNAs (MicroRNA)IBA 11/2013 - 02/2011
4	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2023 - 11/2011
4	Fish OilsIBA 11/2022 - 03/2005
4	LigandsIBA 01/2022 - 11/2006
4	resolvin D3IBA 12/2021 - 01/2016
4	Essential Fatty AcidsIBA 01/2021 - 08/2006
4	LipoxygenasesIBA 01/2020 - 02/2004
4	Prostaglandins EIBA 11/2008 - 09/2004
3	resolvin D4IBA 12/2021 - 01/2016
3	Lipoxygenase (Lipoxygenase-1)IBA 01/2021 - 02/2004
3	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2020 - 06/2009
3	Methacholine Chloride (Methacholine)FDA Link 01/2020 - 01/2007
3	Dinoprostone (PGE2)FDA Link 01/2017 - 04/2003
3	CarrageenanIBA 07/2016 - 08/2009
3	SmokeIBA 12/2015 - 01/2013
3	Interleukin-5 (Interleukin 5)IBA 02/2015 - 09/2002
3	Interleukin-10 (Interleukin 10)IBA 12/2014 - 05/2012
3	EstersIBA 10/2014 - 06/2008
3	17- hydroxy- 4,7,10,13,15,19- docosahexaenoic acidIBA 06/2013 - 01/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2010 - 05/2005
3	AllergensIBA 12/2007 - 01/2002
3	Interleukin-12 (IL 12)IBA 06/2005 - 03/2005
2	Lipocalin-2IBA 01/2023 - 01/2018

Therapy/Procedure

26	Therapeutics 03/2024 - 12/2003
5	Drug Therapy (Chemotherapy) 11/2021 - 04/2012
4	Ligation 01/2017 - 10/2009
3	Intraperitoneal Injections 01/2021 - 08/2009
3	Punctures 01/2017 - 10/2009